Laminopathy Mutations
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Description:
This template maps disease-causing mutations onto the head, rod, and tail domains of the lamin protein, including the Coil 1a, Coil 1b, Coil 2, NLS, and Ig-fold regions. Each mutation is labeled with its position and corresponding amino acid substitution, such as S37L in the head and several substitutions clustered in the Ig-fold domain.
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This template maps disease-causing mutations onto the head, rod, and tail domains of the lamin protein, including the Coil 1a, Coil 1b, Coil 2, NLS, and Ig-fold regions. Each mutation is labeled with its position and corresponding amino acid substitution, such as S37L in the head and several substitutions clustered in the Ig-fold domain.