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BioRender Template
Longevity is Regulated by Highly-Conserved Transcription Factors
Description
This template shows how dietary interventions like calorie restriction and drug treatments such as OXPHOS inhibitors act on insulin/IGF1 receptors and mitochondria to regulate TOR kinase and AMP kinase signaling. These signaling changes activate longevity-promoting transcription factors that drive effector pathways like autophagy and redox homeostasis, ultimately increasing lifespan and healthspan.
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