MASLD MECHANISM
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This template shows how risk behaviors leading to excess calorie intake drive hyperglycemia, elevated fructose, and hyperlipidemia, which increase glucose and fatty acid delivery to the liver. It traces how this promotes hepatic lipid storage and, together with muscle and adipose tissue insulin resistance, leads to oxidative stress, fibrosis, and progression toward hepatocellular carcinoma.
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This template shows how risk behaviors leading to excess calorie intake drive hyperglycemia, elevated fructose, and hyperlipidemia, which increase glucose and fatty acid delivery to the liver. It traces how this promotes hepatic lipid storage and, together with muscle and adipose tissue insulin resistance, leads to oxidative stress, fibrosis, and progression toward hepatocellular carcinoma.