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BioRender Template
Mechanism of Action - Diphtheria Toxin
Description
This template shows the six-step mechanism of action of diphtheria tetanus toxin, beginning with toxin binding to the HB-EGF receptor, clathrin-mediated endocytosis, and protease cleavage of the toxin subunits. It continues through acid-triggered translocation of the A subunit into the cytosol, where it ribosylates EF-2 using NAD, ultimately inhibiting protein synthesis and causing cell death.
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