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BioRender Template
Mechanism of the CRISPR/Cas13 (Type VI) system in bacteria
Creator
s
Description
The Cas13 protein binds to the gRNA, forming a complex. The sgRNA:Cas13 complex scans through single-stranded RNA (ssRNA) until it recognises the complementary protospacer flanking sequence (PFS). When recognition occurs, this leads to non-specific RNA cleavage of the recognised site. Figure as described by (Burmistrz et al., 2020).
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