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Mechanisms by which Tumors Avoid Immune Recognition
Description
This template shows five mechanisms by which tumors avoid immune recognition, including low immunogenicity from loss of MHC-I, tumor antigens being treated as self due to lack of co-stimulation, antigenic modulation through antibody-induced antigen loss, tumor-induced immune suppression via factors like TGF-beta and IL-10, and tumor-induced privileged sites that physically block immune cells. Each mechanism is illustrated with the relevant T cell, APC, or tumor cell interactions.
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