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BioRender Template

Mechanisms of Heart Failure Linked to Mitochondrial Dysfunction

Martina Maritan
3+
Martina Maritan
,
BioRender Team
Creator
s
An editable high resolution scientific image depicting Mechanisms of Heart Failure Linked to Mitochondrial Dysfunction

Description

This template shows how mitochondrial dysfunction in the heart reduces fatty acid oxidation, electron transport chain activity, and the mitochondrial sodium-calcium exchanger, leading to calcium overload and reactive oxygen species generation. These changes converge on mitochondrial permeability transition pore opening, mtDNA damage, and inflammation, driving cell death that feeds back into heart failure.

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