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Mechanisms of Immune Evasion in Head and Neck Cancer by Cancer Stem Cells (CSCs)
Description
This template shows how cancer stem cells in head and neck cancer evade the immune system within the tumor microenvironment through four mechanisms: cell cross-talk via PD-L1/PD1 signaling, surface receptor engagement that suppresses T cells, genetic regulation of CD44 and MHC I expression, and secreted products like exosomes and IL-10/TGF-beta. Each mechanism panel lists its specific effects on T cell recruitment and activity.
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