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Mechanisms Regulating AURKA Expression
Description
This template outlines how AURKA expression is controlled at the DNA, mRNA, and protein levels. At the DNA level, transcription factors like E2F3 and E4TF1 act on the AURKA promoter; at the mRNA level, elements like the IRES and miRISC regulate translation; and at the protein level, APC/C-Cdh1 mediated ubiquitination targets AURKA for proteasomal degradation.
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