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BioRender Template
Membranous ossification vs. endochondral ossification.
Creator
s
Description
MSCs in the bone marrow can differentiate into chondrocytes or osteoblasts. Osteoblasts build bone via intramembranous ossification (red), while chondrocytes undergo proliferation, hypertrophy, and mineralization, leading to bone deposition on the cartilaginous matrix through endochondral ossification (blue). Endochondral ossification forms limb and long bones, whereas membranous ossification forms the axial skeleton.
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