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BioRender Template
Metabolic Adaptations of Dormant Cancer Cells During Cancer Progression
Description
This template shows how primary tumor dormancy arises from external cues like hypoxia, ECM stiffness, and stromal signaling, leading dormant cancer cells toward either therapy-induced dormancy with mitochondrial metabolism and OXPHOS changes or metastatic dormancy involving disseminating tumor cells in a blood vessel. It traces these paths to their outcomes, tumor relapse after therapy withdrawal and secondary tumor formation after extravasation.
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