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BioRender Template
Metastatic Melanoma Molecular Cascades
Description
This template shows the AXL, EGFR, and RTK signaling cascades in a melanoma cell, tracing phosphorylation events through the Ras/B-RAF/MEK/ERK and PI3K/AKT/mTOR pathways that converge on the nucleus to drive cell proliferation, growth, and survival. It also depicts the CTLA-4/B7 and PD-1/PD-L1 immune checkpoint interactions with an antigen-presenting cell and reactive oxygen species contributing to tumor growth.
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