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Microglial Trem2- and CD33-Targeting Antibodies in Alzheimer’s Disease

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Catherine C

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BioRender Team

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Description: This template shows a microglial cell responding to amyloid-beta plaques through two opposing antibody-targeted receptors, an activating antibody that engages Trem2 to turn on Syk/PI3K signaling and an inhibitory antibody that blocks CD33/SHP1 signaling. Together these signals promote degradation of amyloid-beta peptide taken up by the cell.

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What does the Microglial Trem2- and CD33-Targeting Antibodies in Alzheimer’s Disease template show?

This template shows a microglial cell responding to amyloid-beta plaques through two opposing antibody-targeted receptors, an activating antibody that engages Trem2 to turn on Syk/PI3K signaling and an inhibitory antibody that blocks CD33/SHP1 signaling. Together these signals promote degradation of amyloid-beta peptide taken up by the cell.

Is the Microglial Trem2- and CD33-Targeting Antibodies in Alzheimer’s Disease template free to use?

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Yes, every element is fully editable. Icons, labels, colors, arrows, shapes and layout can all be changed to match your preferences or needs using BioRender's drag-and-drop editor. You can add or remove elements to fully customize your use case.

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