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miR-149 Inhibits Lung Metastasis via CSF1

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Ismael Sánchez González

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BioRender Team

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Description: This template was adapted from the original submission. Edits were made to enhance scientific accuracy, optimal usability and/or to meet industry-leading design standards for science communication. miR-149 downregulation in triple-negative breast cancer (TNBC) promotes tumor progression and metastasis by increasing colony-stimulating factor-1 (CSF1)-dependent recruitment and M2 polarization of tumor-associated macrophages (TAMs), and by enhancing reciprocal epidermal growth factor (EGF), amphiregulin (AREG) / CSF1 signaling between cancer cells and TAMs.

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This template was adapted from the original submission. Edits were made to enhance scientific accuracy, optimal usability and/or to meet industry-leading design standards for science communication. miR-149 downregulation in triple-negative breast cancer (TNBC) promotes tumor progression and metastasis by increasing colony-stimulating factor-1 (CSF1)-dependent recruitment and M2 polarization of tumor-associated macrophages (TAMs), and by enhancing reciprocal epidermal growth factor (EGF), amphiregulin (AREG) / CSF1 signaling between cancer cells and TAMs.

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