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Monocyte Recruitment During Tissue Repair
Description
This template compares monocyte recruitment during tissue repair in skeletal muscle after injury versus cardiac muscle after myocardial infarction. In skeletal muscle, Ly6C-high monocytes are recruited early by CCL2 and undergo an in situ phenotypic switch to a Ly6C-low state, while in cardiac muscle, Ly6C-high and Ly6C-low monocytes are recruited sequentially through separate CCL2 and CX3CR1 signals.
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