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Multifunctional Roles of Hydrogen Sulfide (H₂S) in Cellular Physiology
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Description
This figure summarizes the key physiological roles of hydrogen sulfide (H₂S). It regulates (a) energetic metabolism via ATP production in mitochondria, (b) ion channels, including K_ATP, BK_Ca, and L-type Ca²⁺ channels, (c) cell signaling pathways like MAPK, NF-κB, and Nrf-2, (d) protein modifications through persulfidation, and (e) oxidative stress by enhancing antioxidant systems such as GSH. These processes highlight H₂S as a versatile signaling molecule in cellular homeostasis.
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