BioRender Template

Negative Feedback Loops of the Male Hypothalamic-Pituitary-Gonadal (HPG) Axis

Created by

Maggie Drover

Use This Template – Free

No credit card required to sign up.

This template is fully editable in BioRender

Swap in different text, shapes, & icons
Recolor and rearrange every icon, line, & label
Export or share for any use case

Join 4M+ scientists already making publication-ready figures

Description: Illustrates the regulation of male reproductive hormones through a negative feedback loop. The hypothalamus releases GnRH, stimulating the anterior pituitary gland to secrete FSH and LH. LH acts on Leydig cells to produce testosterone, while FSH stimulates Sertoli cells, which support spermatogenesis and release inhibin. Testosterone and inhibin provide negative feedback to the hypothalamus and pituitary, to inhibit GnRH and LH, respectively.

BioRender icons and templates meet journal, grant, and copyright standards. For AI-generated figures, policies vary. Learn More

Not quite the right template? Discover more.

Search thousands of templates across 30+ life-science fields.

Newest templates

ELISA - Reaction View - Indirect - Fluorescent

Hallmarks of Aging (Circle Layout)

ELISA Smart Protocol

ELISA - Well View - Competitive - Antibody - Antibody-labeled - Fluorescent

ELISA - Well View - Competitive - Antibody - Antibody-labeled - Chemiluminescent

ELISA - Well View - Competitive - Antibody - Antibody-labeled - Colorimetric - Conjugated

ELISA - Well View - Competitive - Antibody - Antibody-labeled - Colorimetric - Unconjugated

ELISA - Well View - Competitive - Antigen - Antibody-labeled - Fluorescent

BioRender Template FAQs

What does the Negative Feedback Loops of the Male Hypothalamic-Pituitary-Gonadal (HPG) Axis template show?

Illustrates the regulation of male reproductive hormones through a negative feedback loop. The hypothalamus releases GnRH, stimulating the anterior pituitary gland to secrete FSH and LH. LH acts on Leydig cells to produce testosterone, while FSH stimulates Sertoli cells, which support spermatogenesis and release inhibin. Testosterone and inhibin provide negative feedback to the hypothalamus and pituitary, to inhibit GnRH and LH, respectively.

Is the Negative Feedback Loops of the Male Hypothalamic-Pituitary-Gonadal (HPG) Axis template free to use?

Yes, you can customize this template with a free BioRender account (no credit card required). Paid plans unlock additional export formats, higher-resolution downloads, and publication permissions.

Can I edit or customize this template?

Yes, every element is fully editable. Icons, labels, colors, arrows, shapes and layout can all be changed to match your preferences or needs using BioRender's drag-and-drop editor. You can add or remove elements to fully customize your use case.

Is this template accepted for use in journals, theses, or grant applications?

Yes, BioRender icons and templates meet journal, grant, and copyright standards for publication, and many researchers cite BioRender directly in their figure legends.

How do I cite BioRender if I use this template?

Unlock publication permissions with a paid plan, and include 'Created with BioRender.com' in your figure legend, or cite BioRender directly per your journal's guidelines.

What is Negative Feedback Loops of the Male Hypothalamic-Pituitary-Gonadal (HPG) Axis used for / who typically uses this template?

Researchers and scientists use this template for publications, funding proposals, grant applications, presentations, posters, and more.