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Neurovascular deficits linked to Alzhimer's disease
Description
Neurovascular deficits related to AD include (1) chronic cerebral hypoperfusion (CCH), a reduction in blood flow into the brain that occurs prior to symptomology, (2) neurovascular coupling (NVC) deficits, and (3) blood-brain barrier (BBB) disruption that can be related to (4) cerebral amyloid angiopathy (CAA), characterized by the deposition of Aβ in blood vessels.
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