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BioRender Template
NK vs CD8+ T Cell Killing of Tumor Cells
Description
This template compares CD8+ T cell and NK cell killing of tumor cells, showing that CD8+ T cells kill cancer cells adequately presenting neoantigen via MHC I by releasing perforin and granzyme B, while NK cells target cells with poor MHC I neoantigen presentation. The right panel shows CD8+ T cell-derived IFN-gamma activating dendritic cells and macrophages, which release CXCL9/10 to activate NK cells that then kill the tumor cell via perforin and granzyme B.
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