Try a synonym, or sign up to suggest a template from the app.
BioRender Template
NLRP3 inflammasome pathways
Creator
s
Description
The binding of PAMP/DAMP to its receptors triggers the priming phase of the inflammasome through activation of the NF-κB pathway, which induces the expression of NLRP3 and the precursor form of IL-1β and IL-18. A second signal is needed to induce the oligomerization of NLRP3 and its interaction with ASC, which allows the activation of CASP-1. IL-1β and IL-18 are released, and the GSDMD protein, which forms pores in the membrane that ultimately induce cell death by pyroptosis.
Use this templateThis template is fully editable in BioRender with a free BioRender account — no credit card required to sign up.
Don’t start from scratch.
Create professional scientific illustrations quickly and easily, even without any design expertise
- Get started with a huge library of editable icons and templates such as common biological pathways, anatomy, or genetics.
- Create figures that effectively communicate your research in half the time using our editable icons.
- Use our PDB tool to quickly generate and customize protein structures.
.gif)
