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BioRender Template
Oocyte Maturation Regulation
Description
This template shows the hormonal regulation of oocyte maturation, including GnRH and LH signaling from the brain acting on theca and granulosa cells to drive steroidogenesis, and liver-derived IGF-I acting through IGF-R and follistatin in a local paracrine network with EGF and activin. Both signaling arms converge on oocyte maturation through second messengers such as cAMP, PKA, and Smads.
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