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Opioid Receptor Signaling
Description
This template shows three modes of opioid receptor signaling: a G protein-dependent pathway that lowers cAMP and activates GIRK channels, a beta-arrestin-dependent pathway that recruits GRK and terminates G protein signaling, and a combined Gi/beta-arrestin complex pathway that increases ERK signaling. Each pathway is shown as a separate panel with the opioid receptor embedded in the cell membrane.
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