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p53 Pathways: Regulation of Cell Cycle and Apoptosis

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Fjorilda Dautaj

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Description: Mechanisms of p53 Pathways in Cellular Responses to DNA Damage. This diagram illustrates the multifaceted roles of p53, including activation of checkpoints for cell cycle arrest, facilitation of DNA repair via proteins such as p21 and KU70, and initiation of apoptosis through pro-apoptotic factors like BAX and PUMA. It highlights the delicate balance between maintaining genomic integrity and eliminating irreparably damaged cells

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Mechanisms of p53 Pathways in Cellular Responses to DNA Damage. This diagram illustrates the multifaceted roles of p53, including activation of checkpoints for cell cycle arrest, facilitation of DNA repair via proteins such as p21 and KU70, and initiation of apoptosis through pro-apoptotic factors like BAX and PUMA. It highlights the delicate balance between maintaining genomic integrity and eliminating irreparably damaged cells

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