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BioRender Template
Pathogenesis of Rheumatoid Arthritis
Description
This template shows four steps in the pathogenesis of rheumatoid arthritis, starting with an unknown trigger promoting inflammation and leukocyte recruitment in the synovial membrane. Autoreactive T cells activate macrophages to produce pro-inflammatory cytokines that induce fibroblasts to release MMP and RANK ligand, which activate osteoclasts that destroy cartilage and joint tissue.
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