Pathophysiology of Disseminated Intravascular Coagulation (DIC)

This template shows a flowchart of disseminated intravascular coagulation pathophysiology, tracing how triggering factors cause tissue damage, tissue factor release, and activation of coagulation through the TF-FVIIa complex. This activation leads to platelet aggregation, clotting factor activation, and pro-inflammatory effects that together produce both excess thrombin causing thrombosis and consumption of clotting factors causing haemorrhage, both of which result in organ failure.

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