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pBR322 and pUC19
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Description
• pBR322: One of the first plasmid vectors developed, it contains genes for resistance to Ampicillin (Ampr) and Tetracycline (Tetr) and multiple restriction sites for DNA insertion.
• pUC Series: These plasmids are derived from pBR322 but include a modified region of the lacZ gene. The presence of a polylinker within the lacZ gene allows insertional inactivation, making it possible to screen recombinant colonies via blue-white selection.
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