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PD-1 Blocking Antibodies: Potential Repurposed Drug Candidate for COVID-19
Description
This template compares T cell activation before and after treatment with a PD-1 blocking antibody, showing a dendritic cell presenting antigen via MHC-II to a T cell's TCR/CD4 complex while PDL1/2 engages PD1. Without treatment, PD1 signaling deactivates the T cell, while antibody blockade of PD1 allows T cell activation instead.
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