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Potential Targets for Pancreatic Cancer Immunotherapy

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Omotola Ogundipe

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Description: Immunotherapy activates the body’s immune system to fight cancer. It does this by targeting the tumor microenvironment stromal and altering the activation of immunosuppressive cells, such as regulatory T cells (Tregs), myeloid-derived suppressor cells (MDSCs), and tumor associated macrophages (TAMs), as well as the secretion of cytokines such as transforming growth factor (TGF) and interleukin (IL).

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Immunotherapy activates the body’s immune system to fight cancer. It does this by targeting the tumor microenvironment stromal and altering the activation of immunosuppressive cells, such as regulatory T cells (Tregs), myeloid-derived suppressor cells (MDSCs), and tumor associated macrophages (TAMs), as well as the secretion of cytokines such as transforming growth factor (TGF) and interleukin (IL).

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