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PPAR Signaling Pathway
Description
This template maps how five surface receptors, including IL-1R, TNFR, integrins, a GPCR, and EGFR, feed into intracellular cascades converging on PPAR alpha, beta, and gamma in a macrophage. A boxed legend explains that PPARα is linked to fatty acid metabolism and hepatocarcinogenesis, PPARβ to lipid homeostasis and skin proliferation, and PPARγ to adipocyte differentiation and glucose homeostasis.
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