BioRender Template

Procollagen Export from the ER

Created by

Carol Artlett

•

BioRender Team

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Description:

This template shows two pathways of protein secretion from the endoplasmic reticulum, one for small transmembrane and soluble proteins packaged into standard COPII-coated transport vesicles via the SEC13-SEC31 complex. The other shows secretion of large proteins like procollagen, involving TANGO1, cTAGE5, Sar1-GTP, Sec12, and CUL3-KHL12-mediated ubiquitination to form an enlarged COPII cage and large transport vesicle.

Updated

August 2026

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