BioRender Template

PROTAC controlled CAR-T cell therapy

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Rajamanikkam K

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Description: Model illustrating the control of CAR T cell activity through CAR degradation. A novel CAR T cell safety strategy specifically targets the CAR protein rather than the CAR T cell itself. The PROTAC compound, directed against the bromodomain (BD), degrades the BD-containing CAR protein. Notably, CAR expression is restored upon removal of the PROTAC compound from the cell or system, demonstrating its reversibility.

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What does the PROTAC controlled CAR-T cell therapy template show?

Model illustrating the control of CAR T cell activity through CAR degradation. A novel CAR T cell safety strategy specifically targets the CAR protein rather than the CAR T cell itself. The PROTAC compound, directed against the bromodomain (BD), degrades the BD-containing CAR protein. Notably, CAR expression is restored upon removal of the PROTAC compound from the cell or system, demonstrating its reversibility.

Is the PROTAC controlled CAR-T cell therapy template free to use?

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Yes, every element is fully editable. Icons, labels, colors, arrows, shapes and layout can all be changed to match your preferences or needs using BioRender's drag-and-drop editor. You can add or remove elements to fully customize your use case.

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What is PROTAC controlled CAR-T cell therapy used for / who typically uses this template?

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