BioRender Template

PROTAC: Proteolytic Targeting Chimera

Created by 
Harsh Oza
  •  
BioRender Team
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Description:

This template was adapted from the original submission. Edits were made to enhance scientific accuracy, optimal usability and/or to meet industry-leading design standards for science communication. PROTAC is a progressing technology with a huge scope in protein degradation based therapies for cancer and Alzheimer's like disease. It is a small molecule which has two active domains and a linker. One of the domain binds to the target protein while other one binds to the E3 ligase enzyme, bringing the two proteins in close proximity of each other causing ubiquitination of target protein, followed by its proteasomal degradation. This can allow us to selectively eliminate target proteins.
Updated 
August 2026

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BioRender Template FAQs

What does the PROTAC: Proteolytic Targeting Chimera template show?

This template was adapted from the original submission. Edits were made to enhance scientific accuracy, optimal usability and/or to meet industry-leading design standards for science communication. PROTAC is a progressing technology with a huge scope in protein degradation based therapies for cancer and Alzheimer's like disease. It is a small molecule which has two active domains and a linker. One of the domain binds to the target protein while other one binds to the E3 ligase enzyme, bringing the two proteins in close proximity of each other causing ubiquitination of target protein, followed by its proteasomal degradation. This can allow us to selectively eliminate target proteins.

Is the PROTAC: Proteolytic Targeting Chimera template free to use?

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Can I edit or customize this template?

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What is PROTAC: Proteolytic Targeting Chimera used for / who typically uses this template?

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