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Protease Types and Mechanisms
Description
This template compares the catalytic mechanisms of four protease types in labeled panels A through D: serine proteases using a His-Asp-Ser triad, cysteine proteases using a Cys-His pair, aspartyl proteases using two Asp residues, and metalloproteases using a Zn2+ ion coordinated by His residues and Glu. Each panel shows the active site residues attacking the substrate's peptide bond with curved arrows indicating electron movement.
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