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Reasons for the poor efficacy of oral administration of cytomegalovirus retinitis
Description
In patients with cytomegalovirus retinitis (CMVR), retinal atrophy and choroidal edema occur, leading to retinal vessel attenuation, hemorrhage, and obstruction. Although orally administered antiviral drugs can penetrate retinal vasculature to reach the retina, the aforementioned vascular lesion in the CMVR area result in inadequate blood supply, hindering the full delivery of drugs to the lesion site, thereby compromising therapeutic efficacy.
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