Relapsing/Remitting Experimental Autoimmune Encephalomyelitis (EAE) Mouse Model
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This template shows the timeline for inducing a relapsing/remitting EAE mouse model in SJL mice using proteolipid protein (PLP) plus complete Freund's adjuvant on day 0, followed by pertussis toxin injections on days 1 and 2. It maps disease progression from onset of illness on days 9-14 through partial recovery and relapse occurring in 75-85% of animals by days 20-29.
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This template shows the timeline for inducing a relapsing/remitting EAE mouse model in SJL mice using proteolipid protein (PLP) plus complete Freund's adjuvant on day 0, followed by pertussis toxin injections on days 1 and 2. It maps disease progression from onset of illness on days 9-14 through partial recovery and relapse occurring in 75-85% of animals by days 20-29.