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Revised MitoCat-MitoOx Model
Description
This template compares the canonical oxidative phosphorylation model of glucose-stimulated insulin secretion with a revised MitoCat-MitoOx model showing three sequential steps involving pyruvate kinase, PEP cycling, and plasma membrane ATPase. It details how ATP/ADP ratios at the plasma membrane and mitochondria regulate potassium and calcium channels to trigger insulin release.
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