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BioRender Template
Rheumatoid Arthritis Disease Mechanism
Description
This template shows how mast cells release TNF and tryptase to activate macrophages and synovial fibroblasts, which in turn release IL-1beta and the chemokines CXCL1, CXCL5, and CXCL8. These signals recruit neutrophils, and together the pathway drives joint inflammation characteristic of rheumatoid arthritis.
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