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BioRender Template
RNA-Based Gene Silencing Modalities (HIGS, SIGS, VIGS)
Creator
s
Description
A. HIGS involves the expression of dsRNA by the host itself. The dicer-processed siRNA molecules then leave the nucleus of transgene plants and enter target pest upon feeding. B. SIGS is simply the in-vitro production of dsRNA/siRNA molecules and then its's spray with some nanocarriers on the plant leaves that insects would feed-upon. C. VIGS entails the use of viruses as carriers of dsRNA to either express independently or integrate it into the plant genome.
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