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BioRender Template
Roles of the Complement Cascade in Innate Immunity
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Description
This template was adapted from the original submission. Edits were made to enhance scientific accuracy, optimal usability and/or to meet industry-leading design standards for science communication.
Complement is a collection of soluble proteins undergoing a complex series of combination and cleavage reactions. Ultimately, the major end products resulting from the cleavage of C3 and C5 each play important roles in the innate immune system. C3a and C5a function as anaphylatoxins, recruiting neutrophils and monocytes; C3b serves as an important opsonin while also amplifying the signal of the entire cascade; and finally, C5b combines with other proteins to form the membrane attack complex.
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