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BioRender Template
Selection for High Affinity Mutants at the Germinal Center
Description
This template compares outcomes for germinal center B cells with low versus high antigen affinity mutated surface immunoglobulin. Low affinity B cells fail to cross-link their receptor and undergo apoptosis, while high affinity B cells receive T cell help and receptor cross-linking that sustain proliferation into memory B cells and plasma cells.
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