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Signaling Pathways Underlying EMT and EndMT in Age-related Macular Degeneration (AMD)
Description
This template shows how triggers such as inflammation and oxidative stress activate TGFβ, Wnt, and other receptor signaling to drive Smad, beta-catenin, and RTK-dependent pathways that upregulate EMT and EndMT genes. This process results in myofibroblast formation and contributes to subretinal fibrosis in age-related macular degeneration.
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