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Simplified Molecular Mechanism of Glucose Uptake of Skeletal Muscle at Rest

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Andrea Gomez

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Description: Molecular mechanisms involved in skeletal muscle glucose uptake at rest. IR, Insulin receptor; IRS, insulin receptor substrate; PI-3K, phosphatidylinositol 3-kinase; PIP2, phosphatidylinositol 4,5-bisphosphate; PIP3, phosphatidylinositol (3,4,5)-trisphosphate; PDK, phosphoinositide-dependent kinase; Akt, protein kinase B; AS160, Akt substrate of 160 kDa; GLUT, glucose transporter;

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Molecular mechanisms involved in skeletal muscle glucose uptake at rest. IR, Insulin receptor; IRS, insulin receptor substrate; PI-3K, phosphatidylinositol 3-kinase; PIP2, phosphatidylinositol 4,5-bisphosphate; PIP3, phosphatidylinositol (3,4,5)-trisphosphate; PDK, phosphoinositide-dependent kinase; Akt, protein kinase B; AS160, Akt substrate of 160 kDa; GLUT, glucose transporter;

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