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SOD3 inhibits inflammatory responses.
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Description
Inflammatory mediators activate the host's vascular and leukocyte responses. Vasodilation, accelerated blood flow and increased vascular permeability lead to plasma exudation, followed by a slowing of blood flow and leukocyte exudation which, under the influence of chemokines, aggregates at the site of the injury to remove microorganisms and necrotic tissue. SOD3 inhibits the migration and infiltration of inflammatory cells and reduces the secretion of pro-inflammatory factors in macrophages.
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