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Spleen tyrosine kinase (Syk)-mediated mechanism of action of caspofungin in SARS-CoV-2

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Kazuhiro Itoh

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Description: Syk inhibitors suppress macrophage activation and overproduction of proinflammatory cytokines, thrombus formation, and the release of neutrophil extracellular traps (NETs) caused by SARS-CoV-2, and remove overexpressed mucin-1 from the cell membrane in lung epithelial cells.

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Syk inhibitors suppress macrophage activation and overproduction of proinflammatory cytokines, thrombus formation, and the release of neutrophil extracellular traps (NETs) caused by SARS-CoV-2, and remove overexpressed mucin-1 from the cell membrane in lung epithelial cells.

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