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BioRender Template
Stages of Wound Healing
Creator
s
Description
The figure illustrates wound healing stages. First, platelets activate at the injury site, triggering clotting and coagulation. Next, inflammatory mediators recruit macrophages and neutrophils, releasing cytokines (IL-1β, IL-6, IL-8, IL-10, TNF-α, MMP-8, TGF-β1, bFGF). Resident fibroblasts then migrate, proliferate, and differentiate into myofibroblasts. Finally, ECM components (hyaluronan, elastin, collagen) are produced, leading to wound healing and tissue remodelling.
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