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BioRender Template
Summary of the impact of microglial lipid droplet (LD) accumulation in AD.
Creator
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Description
Compared to normal controls and APOE3/3 AD patients, ACSL1+ microglia identified in APOE4/4 AD patients are enriched with triglyceride LDs, which are distributed around the core or the periphery of Aβ plaques. These cells exhibit lysosomal accumulation and reduced phagocytosis.
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