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BioRender Template
T Cell Co-stimulation and Co-inhibition
Description
This template shows T cell co-stimulation, where MHC-TCR/CD3 signaling combined with B7-1/B7-2 binding to CD28 leads to T cell activation, contrasted with co-inhibition, where B7-1/B7-2 instead bind CTLA-4 and lead to T cell downregulation. Both pathways are shown occurring at the interface between an antigen-presenting cell and a T cell.
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