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BioRender Template
T Cell Differentiation into Various Functional Subtypes
Creator
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Description
This template was adapted from the original submission. Edits were made to enhance scientific accuracy, optimal usability and/or to meet industry-leading design standards for science communication.
Polarizing cytokines activate distinct transcription factor (TF) cascades within naïve CD4+ T cells and influence T cell differentiation into distinct effector T cell subtypes. T helper (Th) 1, Th2, and Th17 effector cell subsets are characterized by the expression of distinct TFs, namely T-bet, GATA3 and RORγt, respectively, that drive the production of signature effector cytokines specific to each Th subset. These effector cytokines are important in mediating responses to an array of pathogens.
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