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BioRender Template
Tamoxifen Metabolism
Description
This template shows the metabolic pathway converting tamoxifen into its active metabolites through the liver enzymes CYP3A4/5 and CYP2D6, forming N-desmethyltamoxifen and 4-hydroxytamoxifen as intermediates. Both intermediates are then converted by the other enzyme into endoxifen, the final active metabolite, with chemical structures shown at each step.
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