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Targeting Neutrophils in Cancer: The Pro- and Anti-tumor Activities of Neutrophils
Description
This template shows strategies for targeting neutrophils in cancer, split into approaches that block pro-tumor neutrophil activity, such as targeting CD33, inhibiting CXCR2, and blocking G-CSF/TNFa signaling or ROS production, and approaches that promote anti-tumor neutrophil activity, such as interfering with inhibitory checkpoints and using IgA- or Fc-modified therapeutic antibodies. Each strategy is labeled A through H around a central tumor cell cluster.
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